The open doctoral student positions are within the “SKELMET” TP4-project:
“Impact of inflammatory mechanisms on osteoblast-metastatic tumor cell interaction“
1 doctoral student (PhD), TV-L E13/65% for 3 years, starting August 2011
Employment of a PhD student (biologist, biochemist holding a Diploma/Master degree), who will perform in vitro studies concerning the role of cytokines, their inhibitors and TRAIL-receptors using several techniques such as cell culture, ELISA, immunostaining, Western blot, knock-down experiments, functional assays (invasion assays, migration assays, proliferation, osteoblast differentiation assay). The ambitious plans for the in vitro experiments require a highly motivated team member, who is able to communicate with the external cooperation partners. A background in molecular, cell biological, and biochemical methods is mandatory.
1 doctoral student (veterinary medicine or other), TV-L E13/65% for 3 years, starting August 2011
For the planning and carrying out the ambitious and complex animal experiments in this project, employment of a veterinarian or a PhD student, who is striving for a demanding doctoral thesis. Our lab has a long-standing history of successful integration of veterinarians in research projects facilitating complex in vivo model systems for the investigation of tumor progression and metastasis. To date, five doctoral theses in veterinary medicine have been successfully supervised. The applicant will directly cooperate with surgical fellows in the highly demanding orthotopic tumor inoculation as well as tumor resection techniques in continuation of the clinically adapted tumor model established in our laboratory. Moreover, the veterinarian or PhD student will also supervise animal care and perform the application of pharmacological substances in animals. Furthermore, she/he will perform and supervise and evaluate the in vivo molecular imaging analyses of living anaesthetized expe!
rimental animals. The successful candidate will come with respective interests for sophisticated in vivo tumor models and also require basic experience with cell culture techniques and histological and microscopical methods including immunohistochemistry.