A graduate student position is open for january 2012 to carry out a Ph.D. thesis in cheminformatics. Applicants must hold a Master's degree in chemistry, biochemistry, informatics, mathematics, or related areas, and have a strong interest in computational work, including programming and data management. The project involves exploration of chemical space by enumeration and mapping of very large databases such as the "chemical universe database" GDB, the largest virtual fragment collection for drug discovery developed by our group, see www.gdb.unibe.ch
Methoden:
cheminformatics programming (Java)
databases
virtual screening
Anfangsdatum: 1. Januar 2012
geschätzte Dauer: 3-4 Jahre
Bezahlung: Schweizer Nationalfonds
Veröffentlichungen:
Recent publication of the group on this topic: L. C. Blum, J.-L. Reymond, J. Am. Chem. Soc. 2009, 131, 8732-3; .-L. Reymond, R. van Deursen, L. C. Blum, Lars Ruddigkeit, Med. Chem. Commun. 2010, 1, 30-38; L. C. Blum, R. van Deursen, J.-L. Reymond, J. Comput. Aided Mol. Des. 2011, 25, 637-647.
Homepage: http://www.gdb.unibe.ch
The project is connected to drug discovery projects within the NCCR TransCure (www.transcure.org) and the NCCR Chemical Biology (www.nccr-chembio.ch).