a) deciphering the transcriptional and epigenetic mechanisms controlling stem cell fate and functional integration of newborn neurons.
b) the effect of neurodegeneration on the stem cell niche.
We are looking for a highly motivated PhD student with a background in biology/biochemistry/neurobiology. We offer state-of-the art methods and a highly interactive laboratory atmosphere.
Selected publications:
Ehm O et al. RBPJκ-dependent signalling regulates Sox2 expression and is essential for longterm maintenance of radial glia like stem cells in the adult hippocampus. J Neurosci, 2010, 30:13794-13807.
Covic M et al. Epigenetic regulation of neurogenesis in the adult Hippocampus. Heredity, 2010 Mar 24.
Jagasia R et al. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J Neurosci. 2009, 29(25):7966-77
Lie DC et al. Wnt signalling regulates adult hippocampal neurogenesis. Nature 2005;437(7063):1370-5.
----------------------------------------------------------------------
Weitere Einzelheiten zu diesem Angebot erfahren Sie unter
http://www.doktorandenboerse.info/suchen/angebot_ausgabe.php?Angebot_id=7049