Light-inducible systems are very attractive due to the high spatial and temporal specificity they offer. Following the approach used by Wu et al. (Nature 461, 104-108, 2009), we intend to create fusions of photo-activatable domains to proteins of interest to be able to control the function of these latter in space and time.
The aim of the project will be the engineering of genetically encoded, photo-responsive protein switches, to control with light either endogenous cellular processes or the function of synthetic circuits.
We are searching for a highly motivated, enthusiastic, team-oriented graduate student with a background in chemistry/biochemistry and a strong interest in combining different research approaches from disciplines such as cell biology, synthetic biology and quantitative/computational biology. Previous experience with basic molecular and cell biology techniques is an advantage.
Please apply via email to barbara.diventura@bioquant.uni-heidelberg.de with a CV, 1 page letter of motivation and 2 reference letters within a single pdf document.