Dr.sc.hum. position in Experimental Nephrology (50% TV-L 13).
The position is available starting October 1st, 2012 or later in the research group “Functional animal models of hereditary kidney diseases”, at our Molecular Nephrology laboratory. The project will be carried out within the framework of the European Consortium for High-Throughput Research in Rare Kidney Diseases (EURenOmics) funded by the European Union (FP7) at the Center for Pediatrics and Adolescent Medicine, Heidelberg University. Funding for this position can be provided for up to three years.
The research of the group focuses on animal models of mostly hereditary rare kidney diseases. An inducible knock-in mouse model expressing the most common human mutation in podocin, a key gene involved in the regulation of the glomerular filtration barrier, allows us to study drug effects in podocin-mutation associated nephrotic syndrome.
The project is focused on testing the efficacy of novel candidate compounds emerging from in vitro screening studies for their ability to attenuate proteinuria and glomerulosclerosis, characteristic features of the nephrotic syndrome, and to delay progression to renal failure.
The successful candidate will work within an international team of young researchers at a well-known university. The candidate will acquire expertise in conducting animal experiments and a wide array of laboratory methodologies (WB, RT-PCR, IF, IHC, expression microarrays etc.), perform statistical analysis, present results at research meetings and international conferences, and publish research manuscripts in high-ranking scientific journals. Postgraduate education in cutting-edge research technologies will be provided as part of the EURenOmics consortium activities.
Candidates must hold a Diploma or M.Sc. degree in Biology, Biochemistry, Biotechnology or a related field and should be able to work with animals. Very good English communication and writing skills are expected. We are looking for a highly motivated young scientist with a strong interest in pursuing innovative translational research, acquiring comprehensive experimental skills and working in a dynamic team.
Please submit your application and CV to Prof. Dr. Franz Schaefer (franz.schaefer@med.uni-heidelberg.de)
Anfangsdatum: 1. Oktober 2012
geschätzte Dauer: 2-3 Jahre
Bezahlung: 50% TV-L 13
Homepage: http://www.klinikum.uni-heidelberg.de/Nephrologisches-Labor.931.0.html